Strong Results and Improved Guidance Lifted Guardant Health (GH) in Q4

2 hours ago 1

Soumya Eswaran

Tue, January 20, 2026 astatine 7:54 AM CST 3 min read

Fred Alger Management, an concern absorption company, released its “Alger Small Cap Focus Fund” fourth-quarter 2025 capitalist letter. A transcript of the missive tin beryllium downloaded here. The US equity marketplace ended the 4th fourth connected a beardown note, with the S&P surging 2.7%, maintaining its dependable upward momentum. Investors' optimism was supported by better-than-expected firm earnings, the US Federal Reserve’s further involvement complaint easing stance, and a resilient macroeconomic backdrop. Improving clarity connected commercialized argumentation provided further support. Meanwhile, the 4th was characterized by expanding divergence beneath the scale level surface. The enthusiasm for AI concern is facing increasing doubts owed to bottlenecks, financing challenges, and uncertainty implicit its quality to make returns. The steadfast continues to observe secular trends that contiguous charismatic concern opportunities for small-cap stocks. In Q4 2025, Class A shares of the Fund outperformed the Russell 2000 Growth Index. The Utilities and Financials sectors contributed to the comparative show of the Fund successful the quarter, portion the Consumer Discretionary and Information Technology sectors detracted from performance. In addition, delight cheque the fund’s apical 5 holdings to cognize its champion picks successful 2025.

In its fourth-quarter 2025 capitalist letter, Alger Small Cap Focus Fund highlighted stocks specified arsenic Guardant Health, Inc. (NASDAQ:GH). Guardant Health, Inc. (NASDAQ:GH) is simply a precision oncology company. On January 16, 2026, Guardant Health, Inc. (NASDAQ:GH) banal closed astatine $112.14 per share. One-month instrumentality of Guardant Health, Inc. (NASDAQ:GH) was 10.66%, and its shares gained 205.89% of their worth implicit the past 52 weeks. Guardant Health, Inc. (NASDAQ:GH) has a marketplace capitalization of $14.564 billion.

Alger Small Cap Focus Fund stated the pursuing regarding Guardant Health, Inc. (NASDAQ:GH) successful its 4th fourth 2025 capitalist letter:

"Guardant Health, Inc. (NASDAQ:GH) is simply a molecular diagnostics institution specializing successful liquid biopsy tests for oncology applications. Unlike accepted tissue-based tests, Guardant’s liquid biopsies usage humor samples, enabling faster results and improved diligent comfort. The company’s tests see broad genomic profiling, crab diagnosis, and attraction monitoring. Shares contributed to show aft the institution delivered beardown fiscal 3rd 4th operating results and raised full-year 2025 gross guidance, signaling stronger-than-expected momentum crossed Oncology, Screening, and Biopharma & Data."